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A 50-year-old female asked:

Hello doctor i suffer from rhumatoid .i am on emthexate2.5 (8pills once a week) and arava leflunomide (a pill every two days ) my liver aches.thank u?

1 doctor answer2 doctors weighed in
Dr. Ahmad M Hadied
Orthopedic Surgery 50 years experience
Severe liver injury: Including fatal liver failure, has been reported in some patients treated with arava (leflunomide). Patients with pre-existing acute or chronic liver disease, or those with serum alanine aminotransferase (alt) > 2xuln before initiating treatment, should not be treated with arava (leflunomide). Use caution when Arava (leflunomide) is given with other potentially hepatotoxic drugs. Also emthexate2.5 have liver sisde effects but as much.
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Dr. Dan Fisher
Dr. Dan Fisher commented
Internal Medicine 28 years experience
You should be monitored regularly for liver toxicity while on these meds.
Jan 13, 2013
Last updated Jun 24, 2014


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