A member asked:

Can a person who does not have epilepsy become epileptic due to antibiotics or do they have to have a history of epilepsy?

4 doctors weighed in across 2 answers
Dr. Michael Ein answered

Specializes in Infectious Disease

Yes they can: Some antibiotics lower the seizure threshold enough to cause seizures in patients that are not epileptic. Giving too high a dose of carbepenam antibiotics like Invanz (ertapenem) or imipenem especially to a patient with renal insufficiency is a relatively common cause. Giving too high a dose of penicillin or cephalosporin drugs can do the same.

Answered 6/26/2014

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Not an association: Epilepsy is a clinical condition of a risk for epileptic seizures. We all can experience a seizure under severe toxic conditions, but this is a specific toxic event, not epilepsy. Antibiotics are quite safe but can be associated with a toxic infection or allergic reaction that can produce a seizure like event. Antibiotics are not a cause for epilepsy.

Answered 10/29/2012

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