A member asked:

In stage 4 ovarian cancer, what does it mean if after several chemo treatments, if your ca-125 stays same?

7 doctors weighed in across 2 answers
Dr. Devon Webster answered

Specializes in Medical Oncology

Hard to say: If your ca-125 was very elevated to start with, and it's staying the same, that means the ovarian cancer cells aren't growing, which is good! of course you'd feel better if your ca-125 was going down, but that can take some time. If your ca-125 was in the normal range to start with, or only mildly elevated, it might not be an accurate marker for your cancer. How you feel is very important!

Answered 11/4/2018

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Ovarian cancer: If a ca 125 does not return within the normal range after surgery and chemotherapy, it is worrisome for resistant or residual disease. However, ca 125 alone is not diagnostic.

Answered 3/2/2016

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