Can lupus cause your period to get messed up?

Yes: Menstrual irregularity is common in women with sle particularly in those treated with immunosuppressive drugs. There is also some evidence sle itself may cause hormonal changes which give rise to menstrual irregularity. Heavy menses can be seen with low platelet counts, steroid therapy and in anitphospholipid antibody syndrome.

Yes: There can be changes in the menstrual cycle due to the disease process itself as well as due to the medications you might be using to treat the lupus.