A 44-year-old member asked:
Is diphenhydramine hydrochloride and doxylamine succinate ok together?
2 doctor answers • 4 doctors weighed in
Anesthesiology 50 years experience
Caution Required: Both drugs have similar "mechanisms of action." therefore, the effects they produce are "additive" and, in theory, can pile up to create more effects than would be predicted if each drug were taken by itself...Almost as if 1+1=3! both drugs produce sedation and have anti-histamine properties. So, excessive sleepiness or agitation can happen. Be cautious..Speak to your provider or pharmacist!
5.5k viewsReviewed >2 years ago
Anesthesiology 36 years experience
5.4k viewsAnswered >2 years ago
A 35-year-old member asked:
What is difference between diphenhydramine hydrochloride and doxylamine?
1 doctor answer • 1 doctor weighed in
Pediatric Hematology and Oncology 54 years experience
Very similar: Both have anti-allergy property and sedative property. Doxylamine seems to be marketed more for its sedative, or sleep medicine effects, while diphenylhydramine seems to be marketed for more anti-histamin effect.
4.3k viewsAnswered >2 years ago
Last updated Sep 10, 2019
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