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A 34-year-old member asked:

Do all stage 1 breast cancer patients without lymph node involvement have to take chemo?

1 doctor answer3 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
On the contrary: The decision to recommend chemotherapy is based on the stage of the cancer, the pt's age, as well as the molecular features, including the estrogen-, progesterone-, & her2/neu receptor status +/-oncotype-dx recurrence score. Stage i-, ln(-) pts may have no chemo-, hormonal rx, or chemotherapy recommended based on the above factors.

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A 24-year-old member asked:

Should stage 1 breast cancer patients with no lymph node involvement generally receive chemo?

3 doctor answers6 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
Sometimes: While the prognosis for stage 1 breast cancer is excellent, many women may benefit from traditional chemotherapy. This is dependent on the age of the patient, whether the tumor is hormone-sensitive, if the her2/neu receptor is overexpressed, and, in select cases, what the oncotype-dx score is. While "negative" lymph nodes are very encouraging, some breast cancers may travel via the bloodstream.
Dr. Andrew Turrisi
Radiation Oncology 47 years experience
I completely agree with Dr Rosen's answer.
Jul 11, 2012
A 46-year-old member asked:

Is it true that stage 1 breast cancer patients with no lymph node involvement recommended to take chemo?

1 doctor answer2 doctors weighed in
Dr. Sabha Ganai
Surgical Oncology 20 years experience
It Depends: Typically it depends on the receptor status (estrogen/progesterone/her2) and the size of the tumor. Tumors greater than a centimeter are generally prescribed chemotherapy, although er/pr+ patients may just get hormonal therapy. The oncotype assay is sometimes used to decide on equivocal cases on when to give chemo. You might want to ask your doctors if this is right for you.
A 39-year-old member asked:

Are all stage 1 breast cancer patients with no lymph node involvement recommended to take chemotherapy?

2 doctor answers7 doctors weighed in
Dr. Barry Rosen
General Surgery 34 years experience
On the contrary: The decision to recommend chemotherapy is based on the stage of the cancer, the pt's age, as well as the molecular features, including the estrogen-, progesterone-, & her2/neu receptor status +/-oncotype-dx recurrence score. Stage i-, ln(-) pts may have no chemo-, hormonal rx, or chemotherapy recommended based on the above factors.

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Last updated Dec 9, 2013

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