Hot vs. cold nodule: Iodine uptake by thyroid tissue depends on functioning cells. The most common use for thyroid scan is to assess if a nodule is functional or not. A functional/hot nodule may cause hyperthyroidism but is not likely to be malignant. See this site for more info. http://www.nlm.nih.gov/medlineplus/ency/article/003829.htm.
Answered 10/20/2012
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