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A 30-year-old member asked:

Is there a difference between adrenal insufficiency vs. addison's?

1 doctor answer6 doctors weighed in
Dr. Vered Lewy-Weiss
A Verified Doctoranswered
A US doctor answeredLearn more
Can be the same: Addison's disease is primary adrenal insufficiency and implies destruction of the part of the adrenal gland which makes cortisol. Secondary adrenal insufficiency is when the pituitary gland doesn't make enough acth, a hormone which signals the adrenal gland to make cortisol.

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Rockville, MD
A 40-year-old female asked:

What is the difference between addison's disease & just having adrenal insufficiency?

1 doctor answer2 doctors weighed in
Dr. Gerald Mandell
Nuclear Medicine 52 years experience
Usually same: Addison’s disease (also chronic adrenal insufficiency) is a rare, chronic endocrine disorder in which the adrenal glands do not produce sufficient steroid hormones (glucocorticoids and often mineralocorticoids). With a number of relatively nonspecific symptoms, such as abdominal pain and weakness, but under certain circumstances, can be life-threatening.Addison's disease occurs in all age groups.
A 32-year-old member asked:

What is the difference between addison's disease and primary adrenal insufficiency ?

2 doctor answers6 doctors weighed in
Dr. Vered Lewy-Weiss
A Verified Doctoranswered
A US doctor answeredLearn more
Can be the same: Addison's disease is primary adrenal insufficiency and implies that the immune system is attacking the part of the adrenal gland which makes cortisol. Primary adrenal insufficiency doesn't have to be autoimmune, however. Secondary adrenal insufficiency is when the pituitary gland doesn't make enough acth, a hormone which signals the adrenal gland to make cortisol.
A 29-year-old member asked:

Is adrenal insufficiency the same as addison's disease?

2 doctor answers6 doctors weighed in
Dr. Susan Wingo
Endocrinology 33 years experience
Not exactly: Addison's disease is one very specific cause of adrenal insufficiency, in which the immune system makes antibodies directed at adrenal proteins which end up destroying the adrenal glands. There are many other causes of adrenal insufficiency including bleeding or infection of the adrenals glands, destruction from cancers that have spread there, or failure of the pituitary to stimulate the adrenals.
A 34-year-old member asked:

What is primary adrenal insufficiency (addisons disease)?

2 doctor answers4 doctors weighed in
Dr. Vered Lewy-Weiss
A Verified Doctoranswered
A US doctor answeredLearn more
Adrenal cortex: The adrenal cortex makes lots of hormones. Very important are cortisol and aldosterone which help maintain life and salt balance. Addison's disease is caused by adrenal cortex damage rendering it unable to make these hormones anymore, mostly autoimmune cause in us. Patients often have a bronzed look. Hydrocortisone replacement is a lifesaving necessity. Fludrocortisone may also become necessary.
A 32-year-old member asked:

Is it true that addisons disease and adrenal insufficiency are the same?

2 doctor answers3 doctors weighed in
Dr. Mazen Kherallah
Infectious Disease 34 years experience
Addison: Addison disease is the decreased function of the adrenal gland with decreased level of aldosterone.

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Last updated Dec 9, 2013

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