A member asked:

I know depakote has a side effect of severe weight gain what is the percentage rate of people who have gained weight while taking it?

3 doctors weighed in across 2 answers
Dr. John Baker answered

Specializes in Neurology

Dpk: I use departed a lot but probably less than I should due to weight gain. Most people don't gain weight on it, esp if they eat exactly the same on it than they ate off it. But my crude estimate would be 40% of people do. Sometimes those it is being used in are predisposed to the weight gain with little activity level or attention to food intake. 40% is my opinion, not from trials.

Answered 5/1/2016

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Depakote: Per Drugs.Com it is common with (1% to 10%) of people taking Depakote experiencing weight loss/gain & /or increased appetite.

Answered 9/13/2019

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