Very Doubtful: The only possible correlation with testosterone would be through dehydration and coincidental liver disease. An on-line study showed no reports of elevated sex hormone binding globulin (linked to testosterone levels) and mucinex (guaifenesin). If you had a hypersensitvity reaction that involved the liver testosterone could go down.
Answered 1/24/2014
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Not to my knowledge: If there is any effect of Mucinex (guaifenesin) on testosterone levels or the androgen axis, it is not felt to be strong (or widely known).
Answered 2/17/2015
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