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A member asked:
Is it still possible to have asthma with a neg methcholine challange? what if cellular changes indicating asthma is seen on bronchoscopy?
6 doctors weighed in across 2 answers
Yes: A mcct can help to evaluate for asthma but is not 100% accurate especially if you are having symptoms. There are other tests or possibly just trying therapy for a short period of time to see if there is a noticeable improvement. Also look into something known as cough variant asthma.
Answered 2/19/2015
5.6k views
It is possible : Traditionally methacholine challenge negativity was termed as a gold standard result suggestive of absent asthma. However if the test was done while you were on asthma treatment ( inhalers etc) changes the equation . In that context it could be a false negative test result . There are no diagnostic "cellular" changes in bronch due o asthma though high eosinophil count could be seen . Talk to doc.
Answered 1/14/2016
5.2k views
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