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A 48-year-old member asked:

Is the glipizide more effective than glyburide and januvia (sitagliptin)?

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Dr. David Geffner
Endocrinology 54 years experience
No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor.

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Last updated Aug 10, 2018

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