A member asked:

Is deprenyl any safer than other maois for depression? if i take it and accidentally eat a small amount of tyramine containing food, will i die?

6 doctors weighed in across 4 answers

Use MAOIs cautiously: Effects of a drug depend on the dose and the person taking it. Read the list of all other meds and foodstuffs you must avoid carefully. Yes, you can die from a hypertensive crisis.

Answered 3/5/2016

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Use MAOIs cautiously: Effects of a drug depend on the dose and the person taking it. Read the list of all other meds and foodstuffs you must avoid carefully. Yes, you can die from a hypertensive crisis.

Answered 1/24/2015

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Doubtful: There is a great deal of concern about maoi's such as deprenyl/selegiline. The concern is that ingesting foods such as smoked meats, aged hard cheeses, and fava beans can lead to a hypertensive crisis. However, ingesting relatively small amounts is unlikely to cause a problem, especially if you are on a small dose or the selegiline patch. Nonetheless, it's a good idea to be careful.

Answered 4/29/2018

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Yes--but: In low doses you don't have to b as careful about tyrannies but in my experience it isn't as effective as Nardil (phenelzine) which requires more caution about diet & potential interactions.

Answered 9/13/2019

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