A 36-year-old member asked:
What is the function of the extra domain in ige & igm?
1 doctor answer • 1 doctor weighed in
Dr. Stevan Cordasanswered
Internal Medicine 58 years experience
Trick question: Are you studying immunology? The extra domain on ige indicates a unique role for the C2 domain in the interaction between ige and fcri. C2 reduces the off-rate of the ige/fcri, thereby resulting in a more stable complex. It is felt that the domain on igm co-contributes to the pentamic structure production.
5.5k viewsAnswered >2 years ago
Last updated Feb 13, 2015
People also asked
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Disclaimer:
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.