Raymore, MO
A 37-year-old female asked:
Started savella, (milnacipran) twice a day, how many hrs should be in between doses?
3 doctor answers • 7 doctors weighed in

Dr. Cyma Khalilyanswered
Psychiatry 37 years experience
TWICE DAILY: Half life of savella (milnacipran) is 6-8 hours so you can take one in the morning and a second one in the evening no greater than 12 hours apart. Do not have to be super strict about the timing. Good luck!
Created for people with ongoing healthcare needs but benefits everyone.
5.6k viewsReviewed >2 years ago

Dr. Grace Akoh-Arreyanswered
Pharmacy 18 years experience
8-10 hours: Allow about 8-10 hours between doses.( its activity last about 8-10 hours). Be consistent so chose the times that work well for you. Be sure to report any behavior changes with your physician. Savella (milnacipran) may be taken without food, however some patients may tolerate it better if taken with food.
Created for people with ongoing healthcare needs but benefits everyone.
5.6k viewsReviewed >2 years ago

Dr. David Hardinanswered
Wound care 38 years experience
10-12 hours: There is some degree of forgiveness to the times but the closer to 12 hours apart the better.
Created for people with ongoing healthcare needs but benefits everyone.
4.9k viewsReviewed >2 years ago
Last updated Nov 24, 2016
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