Difficult: Hallucinogenic mushrooms contain the active compound psilocybin, which can be detected in urine and serum -- but not for long. Psilocybin is water soluble and would be gone within a few days of use. You'd need a specialized urine test looking for psilocybin; standard ones don't test for this compound. A specific urine test for this can usually detect mushroom use within the last 1-3 days.
Answered 9/7/2019
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