A member asked:

How much of a topical application of retin-a 0.5mg is absorbed into a woman's bloodstream and is such quantity teratogenic?

A doctor has provided 1 answer

Minimal: Studies of tretinoin cream have shown maternal blood levels 2-48hr after application to be essentially zero. However, because of significant problems with the oral form, the topical med is considered a category c , a group where no long term studies during pregnancy can verify its safety.

Answered 9/4/2012

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