A 39-year-old member asked:
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are all stage 1 breast cancer patients with no lymph node involvement recommended to take chemotherapy?

2 doctor answers
Dr. Barry Rosen
33 years experience General Surgery
On the contrary: The decision to recommend chemotherapy is based on the stage of the cancer, the pt's age, as well as the molecular features, including the estrogen-, progesterone-, & her2/neu receptor status +/-oncotype-dx recurrence score. Stage i-, ln(-) pts may have no chemo-, hormonal rx, or chemotherapy recommended based on the above factors.
Answered on Oct 16, 2014
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3 thanks
Dr. Richard Orr
43 years experience Surgical Oncology
No: Most important factors are tumor size, age and overall health, estrogen receptor status and her-2-neu status. In general, most young healthy people with a tumor greater than 1 cm will receive chemo and/or hormonal therapy. Smaller tumors are treated if er negative or her-2 positive. Some small er+ tumors are treated with chemo, but the relative benefits are smaller - an oncotype DX is helpful.
Answered on Oct 15, 2014
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3 thanks

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