A member asked:

Is the thyroid stimulating immunoglobulin in the blood an excellent indicator of grave's disease?

4 doctors weighed in across 2 answers

An indicator: Lab tests are essential in making diagnoses, but need to be interpreted in the clinical context. Thyroid stimulating immunoglobulins are important in the etiology of graves disease, but graves disease is a clinical diagnosis. A person can have thyroid stimulating immunoglobulins and not have any disease. See the site below: http://www.Mayomedicallaboratories.Com/test-catalog/print/8634.

Answered 8/29/2012

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LATS: Long acting thyroid stimulating antibody is one of the known antibodies that can result in graves disease. This antibody attaches to the thyroid follicular cells, causing them to increase their creation and secretion of thyroid hormone. This results in an elevation of T4 or t3, (liothyronine) and so you have hypermetabolism (increased metabolism). You should have a tsh, t4/t3, (liothyronine) and antibodies tests to confirm.

Answered 1/15/2015

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