Depends on situation: The goal of a humidifier is to raise the humidity in a given space. If the humidity outside your home is low, opening the window increases the work the humidifier must do to be effective (as you humidify outside). If the humidity outside is higher, why use the humidifier if you can open the window.There is no specific safety issue requiring an open window during their use.
Answered 2/26/2019
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