What is braf ?

Protooncogene: It is a member of the raf kinase family. It regulates cell pathways that affect cell division. Seen commonly in colon cancer but it's role is still inconclusive. Now patients with kras mutations do not respond to certain medications but the braf mutation is still not clear. There are some companies looking at braf inhibitors for cancer but none close to real clinical use yet . Hope this helps.

A gene : This is a gene is involved in growth and differentiation. It can be mutated and involved in some cancer cell growth systems. There are now drugs that impact on mutations of this gene and impact on growth of cancer.

Signaling protein: Braf is a gene that is frequently mutated in cancers (for example melanoma and colon cancer). It is classified as an oncogene, which is a normal gene that can become mutated and/or overexpressed to drive a cancer cell to grow uncontrollably. There are some very promising chemotherapies that specifically target certain mutations of braf. For treatment, it is helpful to know if braf is mutated.