A member asked:

How will 100 mg of clomid impact ovulation versus 50 mg of clomid? my wife is on her 2nd cycle as the 50 mg didn't work. we've been trying for 1.5 years, so i hope clomid works. losing hope that we'll get pregnant.

3 doctors weighed in across 2 answers

Clomid (clomiphene): When using Clomid (clomiphene) the lowest possible dose that induces ovulation or the effect that you desire is the best possible dose. Higher doses of Clomid (clomiphene) may adversely affect the cervical mucus and the endometrial lining.

Answered 6/24/2014

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Well: You have to go up on the dose. Metformin at 1500 mg per day in divided doses ( get xl and go up slow) can increase chances Clomid (clomiphene) would work at lower doses but you can go up to, i think, 200 mg, but look that up. There are other options. Ovarian drilling is an outpatient surgery where small holes are placed, under anesthesia, in the ovarian cortex. Look that up with metformin, it'll happen.

Answered 6/5/2016

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