Could taking antibiotics like doxycycline, bactrim and macrobid have caused my baby to have a complete agenesis of the corpus callosum? the drugs were prescribed by the doctor for e-coli and ut infections and taken during the first trimester of pregnancy

Possible: Agenesis of the corpus callosum is associated with abnormal development of the brain between 3rd and 12th week of pregnancy. Alcohol for example is a known substance associated with this abnormaility. Antibiotics are a possibility, but I do not believe there has been a defininite link established. Macrodantin is class b, pretty safe, Bactrim (sulfamethoxazole and trimethoprim) is c and Doxycycline d.

No apparent link: The meds above have not been linked to acc. Any triggering process is in play at or before the 4th month, when the cc normally forms.Acc has been found as a sporadic event, or showing autosomal dominant, recessive or x linked forms of inheritance.It can occur in normal people or as part af a significant syndrome or chromosome defect. Genetic eval & counseling are indicated for all cases.