What are the effects of salvia divinorum or datura stramonium?

Generally unpleasant: Salvia is a potent kappa opioid stimulator. Wiki it. It will change your mental state, but it's generally un-fun. It is an anti-opioid. Datura is just dangerous. A very close family member took that as a teenager and never got over it. Really. My brother is no longer alive.

Salvia & Datura: These come from 2 different families, but both are commonly used as hallucinogens. Salvia divinorum contains the extremely potent, non-alkaloid hallucinogen salvinorin a. Along with hallucinations it can cause slurred & slow speech, confusion, paranoia, depersonalization, & blunted affect. Datura stramonium contains belladonna alkaloids, which can induce anticholinergic poisoning & death.