A member asked:

What is the cause of alzheimers?

4 doctors weighed in across 2 answers

Unknown: In spite of a great deal of research and many theories, the definite cause still eludes us.

Answered 8/18/2012

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Dr. Ruth Seaman answered

Specializes in Psychiatry

Many causes: Try Alzheimer's.org - they have nice details. Abnormal levels of a bad protein called AB42 in oligomer form along with hyperphosphoryated tau. TDP-43 and abnormal progranulin levels and others may also play a role in some cases. Inflammation is pivotal. Genetics defects can be in coding for an enzyme that forms AB42, or one that helps clear it from the brain.

Answered 4/6/2015

3k views

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