A member asked:

Does rituximab lower your immune system?

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Dr. Herbert Duvivier answered

Specializes in Hematology and Oncology

Yes: Rituximab (rituxin) is a monoclonal antibody to cd20 an antigen located on lymphocytes. One consequence of using this drug is a drop in lymphocyte numbers (bad cells and good cells). This decline lowers the effectiveness of the immune system for a period of time.

Answered 1/16/2021

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Dr. Herbert Duvivier answered

Specializes in Hematology and Oncology

Yes: Rituximab is directed against an antigen found on lymphocytes (cd20). It attaches to this antigen and causes destruction of the lymphocyte. Its action is indiscriminate therefore the lymphocyte population is transiently decreased leading to a lowering of the function of the immune system for brief periods of time.

Answered 3/23/2020

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