A member asked:

Could symbyax (fluoxetine and olanzapine) contribute to a fatty liver?

6 doctors weighed in across 2 answers

Uncommon.: While elevations in liver enzymes can occur, development of fatty liver changes as a direct result of fluoxetine/olanzapine is unlikely. However increased caloric intake/weight gain and Insulin resistance can lead to fatty liver and Olanzapine has been linked to these events.

Answered 10/17/2017

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Agree w Dr Reynolds: Per Drugs .Com Rare liver fatty deposit occurs in less than 0.1%. However, overall weight gain can impact liver fat.

Answered 3/22/2020

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