A 46-year-old member asked:
what does "her 2 neu" mean?
3 doctor answers
Dr. Barry Rosen answered
34 years experience General Surgery
Tumor Marker: Her 2/neu is a cell membrane protein that is overexpressed in as many as 30% of breast cancer patients. Those patients that overexpress this marker tend to have more aggressive cancers, although these patients are preferentially able to be treated with a chemotherapy drug that targets these tumors called herceptin (trastuzumab).
Answered on May 28, 2014
Dr. Steven Rottman answered
18 years experience Plastic Surgery
Breast cancer gene: Her2 (human epidermal growth factor receptor 2) also known as neu, erbb-2, cd340 (cluster of differentiation 340) or p185 is a protein that in humans is encoded by the erbb2 gene. Her2 is a member of the epidermal growth factor receptor (egfr/erbb) family. Amplification or over-expression of this gene has been shown to play an important role in the pathogenesis and progression of certain aggressiv.
Answered on Dec 20, 2014
Dr. Kenneth Liu answered
20 years experience Neurosurgery
Genetic marker. : It is a genetic marker that can be found several kinds of cancer including breast, stomach, and uterine cancer. If the cancer is positive for this marker or exhibits over-amplification of this gene, it can be associated with a more aggressive course.
Answered on Jul 21, 2014
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