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A 24-year-old member asked:
Should stage 1 breast cancer patients with no lymph node involvement generally receive chemo?
3 doctor answers • 6 doctors weighed in

Dr. Barry Rosenanswered
General Surgery 36 years experience
Sometimes: While the prognosis for stage 1 breast cancer is excellent, many women may benefit from traditional chemotherapy. This is dependent on the age of the patient, whether the tumor is hormone-sensitive, if the her2/neu receptor is overexpressed, and, in select cases, what the oncotype-dx score is. While "negative" lymph nodes are very encouraging, some breast cancers may travel via the bloodstream.
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6.3k viewsReviewed >2 years ago

Dr. Andrew Turrisi commented
Radiation Oncology 49 years experience
I completely agree with Dr Rosen's answer.
Jul 11, 2012

Dr. Marci Dietrichanswered
Bariatrics 43 years experience
Depends: If the tumor is hormone positive and or her2 positive there is chemo hormone blockerstypically, radiation, lumpectomy followed by anti hormone meds.On the other hand, triple negative breast cancer stage i will most likely need chemotherapy iv. It is a bit controversial about a tumor less than 5mm, but anything above that has lumpectomy, node bx, and adjuvant chemonow, docs are trying chemo presurg.
Created for people with ongoing healthcare needs but benefits everyone.
6k viewsAnswered >2 years ago

Dr. Travis Kidneranswered
Surgical Oncology 19 years experience
Depends: This depends on the tumor characteristics. Best to discuss this your friendly oncologist.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsAnswered >2 years ago
Similar questions
A 34-year-old member asked:
Do all stage 1 breast cancer patients without lymph node involvement have to take chemo?
1 doctor answer • 3 doctors weighed in

Dr. Barry Rosenanswered
General Surgery 36 years experience
On the contrary: The decision to recommend chemotherapy is based on the stage of the cancer, the pt's age, as well as the molecular features, including the estrogen-, progesterone-, & her2/neu receptor status +/-oncotype-dx recurrence score. Stage i-, ln(-) pts may have no chemo-, hormonal rx, or chemotherapy recommended based on the above factors.
Created for people with ongoing healthcare needs but benefits everyone.
5.5k viewsReviewed >2 years ago
A 46-year-old member asked:
Is it true that stage 1 breast cancer patients with no lymph node involvement recommended to take chemo?
1 doctor answer • 2 doctors weighed in

Dr. Sabha Ganaianswered
Surgical Oncology 22 years experience
It Depends: Typically it depends on the receptor status (estrogen/progesterone/her2) and the size of the tumor. Tumors greater than a centimeter are generally prescribed chemotherapy, although er/pr+ patients may just get hormonal therapy.
The oncotype assay is sometimes used to decide on equivocal cases on when to give chemo. You might want to ask your doctors if this is right for you.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago
A 39-year-old member asked:
Are all stage 1 breast cancer patients with no lymph node involvement recommended to take chemotherapy?
2 doctor answers • 7 doctors weighed in

Dr. Barry Rosenanswered
General Surgery 36 years experience
On the contrary: The decision to recommend chemotherapy is based on the stage of the cancer, the pt's age, as well as the molecular features, including the estrogen-, progesterone-, & her2/neu receptor status +/-oncotype-dx recurrence score. Stage i-, ln(-) pts may have no chemo-, hormonal rx, or chemotherapy recommended based on the above factors.
Created for people with ongoing healthcare needs but benefits everyone.
5.6k viewsReviewed >2 years ago
Last updated Oct 19, 2017
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