Can lyrica (pregabalin) help with my chronic myofascial pain syndrome?

Possibly: Lyrica (pregabalin) does a good job with diabetic peripheral nerve pain, and may be useful with other pain syndromes. Another drug, cymbalta, has now been approved for a variety of non-nerve pain syndromes, and may be a bit more useful with "myofascial pain". You could try either, but high dosage levels may be important, if you can adjust to side effects.