What are some side effects to prisiq?

Varied.: With a medicine like pristiq, (desvenlafaxine) there can be all sorts of side effects. Around 10% of people experience fatigue, constipation, diarrhea, dizziness, difficulty sleeping, nausea, and sweating. As you can tell, it's a pretty broad list, and it all really depends on your body tolerates it. Most side effects go away in about a week, but you should talk with your physician if you're concerned.