A member asked:

What are the possible causes of t2 hyperinensities on an mri of the brain (aside from ms)?

5 doctors weighed in across 2 answers

Non specific: Migraine, hypertension, antiphosphipid syndrome, sjogren, vitamin B12 deficiency, all infectious, vasculitic conditions--or just old age--depending if periventricular and affecting corpus callosum, their number, distribution, age of the patient, enhencement, you can guess---this is very frequent clinical question.

Answered 5/21/2016

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Many perhaps: You describe the presence of leukoariosis, which depending on quantity and location may be a marker for ms, migraine, prior head trauma, "hardening of the arteries"/angiopathy, vasculitis, and even benign coincidental lesions of unclear etiology. However, just to be clear, ms can start with maybe 1 solitary lesion initially, and over a 14 yr history, perhaps 60% of some pts will prove to have ms.

Answered 4/27/2013

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