A member asked:

I want to know if it is safe to.take tramafol.and opana in the same day. not together but one in the morning and one at night?

A doctor has provided 1 answer
Dr. William Newton answered

Specializes in Pain Management

Big difference: There is quite a difference in the strength of these two medications. It is not uncommon to use a different immediate release medication closer to bedtime if your regular medication causes insomnia. You should discuss this with you pain management provider.

Answered 8/7/2012

5.7k views

Thank

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