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A 47-year-old member asked:

what causes itching in renal failure?

2 doctor answers7 doctors weighed in
Dr. Peter Kurzweil
Internal Medicine 50 years experience
Increase urea levels: The kidneys are the cleansing organs through which all the blood flows in and dangerous by products of the body are filtered and removed through the urine. Everything the body needs is returned to the blood from the kidneys. As the kidneys fail, a protein breakdown product called urea builds up, and when high enough builds up in the skin causing itching. Transplant and/or dialysis may follow.
Dr. Fred McCurdy
Pediatric Nephrology and Dialysis 45 years experience
Itching in RF: The main causes in dialysis patients are: 1) drying of the skin due to accumulated waste products such as calcium, phosphorous, and urea not removed by dialysis; and 2) release of the body's internal substance called histamine due to the dialysis process. These are the typical reasons. Excellent source for more: http://kidney.Niddk.Nih.Gov/kudiseases/pubs/expect/#8.

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What is pruritus ani?

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A 44-year-old member asked:

Is there a particular bacteria that causes itchiness?

2 doctor answers3 doctors weighed in
Dr. Steven Machtinger
Allergy and Immunology 44 years experience
Maybe.: Interesting question. Staphylococcus infection of eczematous skin is certainly associated with increased itchiness. But its not clear if the bacteria increases itchiness or simply exploits the skin injured by scratching to cause a secondary infection.
A 36-year-old member asked:

What are the barriers to the assessment of someone with chronic renal failure?

1 doctor answer1 doctor weighed in
Dr. James Cain
Nephrology and Dialysis 36 years experience
Weight and money: Obesity hinders the accurate assessment of renal function as the estimate of renal function is based on normal weight and muscle mass, obesity obscures signs and symptoms of many systemic diseases.Lack of insurance has been an impediment to acquiring the appropriate testing for some of my patients.

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