A member asked:

Explain the effects of warfarin tablets.?

5 doctors weighed in across 2 answers

Effects of Warfarin: Warfarin is a vitamin k antagonist, hence it will block all the vit k dependent clotting factors preventing the formation of the fibrin clot. It effectively delays your blood from clotting. It is important to take the right dose so the blood clotting is delayed to an optimum time. This is done by checking pt (prothrombin or factor ii time) and inr. Details of this will be out of scope.

Answered 1/15/2021

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Anticoagulant: The anticoagulant effect of warfarin is mediated through inhibition of the vitamin k-dependent gamma carboxylation of coagulation factors ii, vii, ix, and x and proteins c and s. This results in the synthesis of immunologically detectable but biologically inactive forms of these coagulation proteins. The anticoagulant effect is delayed until normal clotting factors clear from the circulation.

Answered 8/3/2012

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