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A member asked:

How can chronic myelogenous leukemia cause hepatomegaly?

A doctor has provided 1 answer

Infiltration: The speen does enlarge in this disease. The causes include direct inflitration. Another is production of other blood elements (extramedullary hematopoesis) in the speen in response to either replacement of the marrow with CML or scar. The scarring is called myelofibrosis.

Answered 9/11/2018

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