A 45-year-old member asked:
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Was azt (zidovudine) originally developed for cancer?

1 doctor answer
Dr. William A Biermann
45 years experience in Medical Oncology
Yes: It was originally developed as a nucleoside analog. It was thought that it might lead to false replication of dna in tumor cells. It failed. That goes back to the 60's. Later drugs of this type were tested for retroviruses and the rest is history. There is a nice article from the ny times in 1986.
Answered on Aug 2, 2012

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