Could a bed bug bite cause serious damage to the genitals?

Depends: This depends on whether the bite is becoming infected which includes symptoms of warmth to the touch along with presenting redness and swelling and pain! local reactions to bites can be red, warm, swollen and itchy but generally not painful (unless the patient is itchy the area so much to cause trauma).

Not likely unless : There is a significant allergic reaction or secondary infection from scratching. Have no sx's/signs except for 2 small skin puncture points. A reaction may show from an hr to several days later. It can cause itchy, pink, swollen, lesions w clear center. If hypersensitive blisters may occur. Telltale sign is linear track of lesions from sequential feedings – doesn't always occur. Bites are in areas.