Can you die from nitrous oxide exposure?

Toxic overdose: Yes it can be toxic.The proper amount of oxygen closely monitored by your dentist or anesthesiologist will assure a safe experience. Very safe, however improper percentages of nitrous can cause a medical emergency, heart stress and death. Long term low dose exposure in a dental office from leaky masks is not healthy for dental personal.

Yes, but: Really only if you are inhaling 100% nitrous oxide, because then you are not getting any oxygen. You need oxygen to sustain life.

Yes: People have died while using nitrous oxide recreationally. It is due to the lack of oxygen, not the danger inherent in the drug itself. Professionally administered it is extremely safe. Reducing anxiety actually can make dental procedures safer. Prolonged, excessive exposure to nitrous oxide can cause neurological problems. And it's use during pregnancy and by pregnant team members is unwise.