It's the caffeine: I believe this caution relates to the caffeine present coffee. While combining caffeine with Klonopin (clonazepam) may possibly inhibit klonopin's effectiveness in anxiety treatment, caffeine does not interfere with klonopin's anti-seizure activity.. There is no specific drug drug interaction between caffeine and Klonopin (clonazepam) to my knowledge.
Answered 6/26/2014
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