A member asked:

What happens to the marrow in myelodysplastic syndrome?

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Affects production: Myelo=blood. Dysplasia=abnormal so what happens is the blood is not getting made normally because the blood cells have what is referred to as dyspoiesis. So people can present with low red count, low white count and low platelet count. Treatment either involves transfusions, growth factors or chemotherapy. Sometimes bone marrow transplant is utilized.

Answered 7/21/2012

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Dr. Agos Luca answered

See below...: The bone marrow is usually hypercellular (high cellularity) in mds, similar to leukemia. However, unlike leukemia, most of these abnormal cells cannot get out of the marrow into the peripheral blood (ineffective hematopoiesis). Consequently, the peripheral blood cell counts are abnormally low (cytopenia), unlike leukemia where the white blood cell count is usually highly elevated.

Answered 4/23/2014

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