Is it better to take tylenol (acetaminophen) or motrin for a fever?

Either: Tylenol (acetaminophen) is an antipyretic so it is helpful with fever. Ibuprofen is an anti-inflammatory and addresses both fever and inflammation. With stubborn fevers people often alternate tylenol (acetaminophen) (every 4 hours) and Ibuprofen (can be taken every 6 hours). Some people find one works better than the other for them. Be sure you are drinking well when taking ibuprofen.