A 30-year-old member asked:
Why does acid cause hemolysis?
2 doctor answers • 2 doctors weighed in
Psychiatry 47 years experience
Can be avoided: Acetylsalicylic acid (aspirin) can cause severe hemolytic (i.e., breakdown of red blood cells with release of hemoglobin) anemia in certain individuals who are born with a deficiency in a particular enzyme (glucose-6-phosphate-dehydrogenase -- g6pd), an enzyme needed for rbcs to function properly. Once the triggers are identified (and avoided), you can lead a healthy and active life.
6.1k viewsAnswered >2 years ago
Pediatric Hematology and Oncology 19 years experience
Denatures hemoglobin: In the lab, acidic solutions will denature hemoglobin, causing the red cell to hemolyze. Fetal hemoglobin is more resistant to this. This difference is the basis of a test to determine how much fetal blood is mixed in the maternal blood system of mom's who are rh negative, and thus need rhogam.
5.7k viewsAnswered >2 years ago
Last updated Jul 26, 2012
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