A member asked:

In what way does ethylene glycol cause hemolysis?

5 doctors weighed in across 2 answers
Dr. Michael Depietro answered

Specializes in Pulmonary Critical Care

Does not: At least not in humans. Ethylene glycol is metabolized to a number of toxic compounds that can damage kidney, brain and heart. In animals particularly mice one of these damages red blood cells and causes hemolysis, but for some reason this is very rare in humans. Apparently the human red blood cell is relatively resistant to that particular injury. Still the other toxicities remain.

Answered 2/8/2012

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Least of troubles: Ethylene glycol causes death by acidfying the body and producing crystals in the brain and kidney; there are problem direct toxic effects on some of the metabolic pathways as well. Hemolysis, if it occurs, is the least of these patients' problems. This question appears elsewhere and i wonder if some misguided teacher is asking it. Good luck.

Answered 9/10/2013

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