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A 37-year-old member asked:

What is type 3 von willebrand's disorder?

2 doctor answers3 doctors weighed in
Dr. James Ball
Pediatric Hematology and Oncology 20 years experience
Bleeding disorder: Type 3 VWD is a bleeding disorder, that results in a complete absence of production of vw factor, which is necessary to initiate the clotting process. Its absence causes factor 8 to be consumed quickly. Thus, this is a severe bleeding disorder. It is inherited from both parents. It causes nosebleeds, gum bleeding, menstrual bleeding and joint/muscle bleeding. It is treatable.
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Dr. Joseph Torkildson
Pediatric Hematology and Oncology 40 years experience
Homozygous vWD: Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein. Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood.
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Last updated Jan 28, 2017
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