A member asked:

What is type 3 von willebrand's disorder?

3 doctors weighed in across 2 answers
Dr. James Ball answered

Specializes in Pediatric Hematology and Oncology

Bleeding disorder: Type 3 VWD is a bleeding disorder, that results in a complete absence of production of vw factor, which is necessary to initiate the clotting process. Its absence causes factor 8 to be consumed quickly. Thus, this is a severe bleeding disorder. It is inherited from both parents. It causes nosebleeds, gum bleeding, menstrual bleeding and joint/muscle bleeding. It is treatable.

Answered 9/28/2016

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Homozygous vWD: Pts with type 3 VWD have loss or mutations of both vwf genes, and produce almost no vwf protein. Clinically they behave like severe hemophilia a patients as their factor viii levels are very low as well, since vwf also carries factor viii in the blood.

Answered 1/28/2017

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