What is von willebrand's disease?

Bleeding disorder: Vwd is a decrease in production (usually) of a specific protein required for clotting blood, called vw factor. The actual amount produced varies. Typical symptoms include nosebleeds, heavy periods, easy bruising and bleeding after surgeries. There are treatments for this disorder. This is type 1 and it is the most common bleeding disorder.

Von Willebrand ....: Factor . Vwf is a glycoprotein important for primary hemostasis. It cross links collagen at a site of injury with gpib on platelets. Deficiency leads to failure of primary hemostasis (ie, bleeding). Vwf also protects fviii from degradation. Fviii also promotes clotting. So, vwf deficiency also causes secondary fviii dysfunction. Vwf def has many variants. Severity is variable. Most have type i.