Is it possible to treat an infected ear piercing with neosporin?

May want evaluation.: You may want to have your ear evaluated by a doctor. If it is not responding to over the counter topical antibiotics like neosporin you may have a complicated infection that may require oral antibiotics. It is also very common to have a allergy to a metal in your earring that may seem like an infection but isn't. This may require something other than an antibiotic like a topical cortisone cream.

Maybe: Neosporin contains neomycin and may cause an allergic reaction. Polysporin (bacitracin and polymyxin) does not contain this agent, and is recommended for treating minor skin infections. If the ear lobe is not red, swollen, tender, warm, or draining, topical polysporin (bacitracin and polymyxin) three times per day for seven days may be effective. If any of the above signs are present, systemic antibiotics may be indicated.