A member asked:

Is sam e a good for a natural anti depressant?

A doctor has provided 1 answer
Dr. Pamela Pappas answered

Specializes in Psychiatry

SAM-e: Taking sam-e orally can possibly improve the symptoms of depression. Several clinical studies show sam-e to be more effective than placebo, and at least as effective as tricyclic antidepressants, in trials up to 42 days. Some of these studies are limited by low #'s of patients, inconsistent diagnostic criteria, and short trial length. Dose is 400-1600mg/day -- which can become expensive.

Answered 12/9/2013

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