A 59-year-old member asked:
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is alpha thalassemia trait the same thing as alpha thalassemia?

1 doctor answer
Dr. Robert Kwok
32 years experience Pediatrics
Not quite: Normal people have 4 Alpha globulin genes. Mutations in 1, 2, 3, or all 4 of the genes cause the 4 levels of Alpha thalassemia. One mutation = silent carrier (no symptoms), 2 mutat. = Alpha trait (mild anemia), 3 mutat. = HGB h disease (anemia sometimes needing transfusions), 4 mutat. = bart's disease (fatal before birth in almost all cases; lifelong transfusions needed to survive if born alive).
Answered on Jun 24, 2014
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Related questions:

A 52-year-old member asked:
Dr. James Ferguson
45 years experience Pediatrics
Inherited defect: Our regular hemoglobin is composed of Alpha and beta chains that come together to form working hemaglobin. Alpha thalassemia trait occurs when a perso ... Read More
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3 thanks
A 36-year-old male asked:
Dr. Martin Rubenstein
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No: People with thalassemia tend to absorb extra iron from their diet and the body tries to find ways to make more blood. Sometimes, Folic Acid may be lo ... Read More
A 46-year-old member asked:
Dr. Ed Friedlander
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Nothing: Alpha thal minor is uttery trivial. Manage your asthma and if you choose to marry, be aware of your alpha-thal and the risk that marrying someone else ... Read More
A 39-year-old member asked:
Dr. Louis Cooper
47 years experience Pediatrics
Adaptive?: Not certain what you mean. Alpha Thal trait is a genetic--hereditary finding, which was shared with you by either your Mom or Dad. It is not adapti ... Read More

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