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A 41-year-old member asked:

Is there a difference between benadryl (diphenhydramine) and pseudoephedrine?

2 doctor answers4 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 35 years experience
Yes: Benadry is the brand name for diphenhydramine, an antihistamine. Pseudoephedrine is a decongestant. So definitely a different medication.
Dr. Jack Mutnick
Allergy and Immunology 17 years experience
Benadryl (diphenhydramine) and Sudafed: Benadryl (diphenhydramine) is an antihistamine (blocks the histamine receptor) and sudafed is a decongestant. Basically sudafed grabs a hold of the blood vessels and squeezes them down for a period of time. Hence the reason that rebound congestion and high blood pressure are attributed to this medicine.

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A 39-year-old member asked:

What's the difference between Benadryl (diphenhydramine) and sudafed?

1 doctor answer1 doctor weighed in
Dr. David Martin
ENT and Head and Neck Surgery 28 years experience
Medical questions: Benadryl (diphenhydramine) is an antihistamine, good for allergies and to lessen the drainage during an upper respiratory infection. Sudafed is a decongestant, good for helping you breath through a stuffy nose from a cold, bad allergies or sinus problems. Sudafed can also raise blood pressure, and shouldn't be taken on a regular basis.

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Last updated Dec 28, 2016
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