U.S. doctors online nowAsk doctors free
A 41-year-old member asked:

Is there a difference between benadryl (diphenhydramine) and pseudoephedrine?

2 doctor answers4 doctors weighed in
Dr. Stephen Kimura
Allergy and Immunology 36 years experience
Yes: Benadry is the brand name for diphenhydramine, an antihistamine. Pseudoephedrine is a decongestant. So definitely a different medication.
Dr. Jack Mutnick
Allergy and Immunology 18 years experience
Benadryl (diphenhydramine) and Sudafed: Benadryl (diphenhydramine) is an antihistamine (blocks the histamine receptor) and sudafed is a decongestant. Basically sudafed grabs a hold of the blood vessels and squeezes them down for a period of time. Hence the reason that rebound congestion and high blood pressure are attributed to this medicine.

Similar questions

A 39-year-old member asked:

What's the difference between Benadryl (diphenhydramine) and sudafed?

1 doctor answer1 doctor weighed in
Dr. David Martin
ENT - Head & Neck Surgery 29 years experience
Medical questions: Benadryl (diphenhydramine) is an antihistamine, good for allergies and to lessen the drainage during an upper respiratory infection. Sudafed is a decongestant, good for helping you breath through a stuffy nose from a cold, bad allergies or sinus problems. Sudafed can also raise blood pressure, and shouldn't be taken on a regular basis.
Last updated Dec 28, 2016
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.